Colorado vs. Nebraska odds, line, spread, time: Top expert picks, predictions for Deion Sanders' home debut

The Colorado Buffaloes and Nebraska Cornhuskers will face off in Boulder on Saturday for Deion Sanders' home debut as the Buffaloes' head coach. The game is set for noon ET, and the Buffaloes are 2.5-point favorites.

The Buffaloes are coming off a surprising 34-27 win over TCU in their season opener. Colorado was a 21-point underdog in that game, but the Buffaloes were led by a strong rushing attack and a solid defensive effort.

The Cornhuskers are also coming off a win in their opener, defeating South Dakota State 54-7. Nebraska was led by quarterback Adrian Martinez, who threw for 232 yards and three touchdowns.

The game is expected to be a close one, and the experts are split on who they think will win. Here are some of the top expert picks and predictions for the game:

• Jimmie Kaylor of SportsLine: Colorado -2.5
• Kyle Bonagura of ESPN: Colorado -2.5
• Matt Fortuna of The Sporting News: Colorado -2.5
• Chris Fallica of NBC Sports: Nebraska +2.5
• David Cobb of Action Network: Colorado -2.5

The experts seem to be leaning towards the Buffaloes, but the game is certainly a toss-up. It will be interesting to see how Sanders' first home game as the Buffaloes' head coach goes.

Here are some additional things to watch for in the game:

• The Buffaloes' rushing attack. Colorado ran for 245 yards against TCU, and the Buffaloes will need to establish the run again in order to win this game.
• Nebraska's defense. The Cornhuskers' defense was impressive in their opener, and they will need to keep the Buffaloes' offense in check if they want to win.
• Adrian Martinez. The Nebraska quarterback is a dual-threat playmaker who can beat teams with his arm or his legs. Martinez will need to have a big game if the Cornhuskers want to win.

The Colorado vs. Nebraska game is sure to be a close and exciting one. The experts are split on who they think will win, but the Buffaloes are the slight favorites. It will be interesting to see how Sanders' first home game as the Buffaloes' head coach goes.